一、发病情况：该养殖户饲养的是美系白色獭兔，9月20日发现有8只体重约3.5公斤的母兔发病，22日发病母兔增加到18只，发病率为种母兔饲养量的38%,23日已有3只死亡，死亡率为16%.

First, the incidence of the farmers rearing is the United States Department of White Rex, September 20th found that the incidence of 8 female rabbits only about 3.5 kg in weight, 22 day incidence of female rabbits increased to 18, the incidence rate of female rabbit rearing volume of 38%, 23, 3 rats died, the mortality was 16%.

二、临床症状。病兔精神沉郁，食欲减少或废绝，排出小而坚硬粪便，个别不排粪。

Two. Clinical symptoms. The rabbits in the depression, loss of appetite or waste, discharge of small hard stool, defecation is not individual.

三、长毛兔剖检变化。剖检3只病死兔，肠粘膜有不同程度出血，肠系膜淋巴结肿胀，回肠和盲肠粘膜以及回盲瓣也有不同程度肿胀，其他器官无明显变化。

Three. Changes of necropsy in Angora rabbits. 3 rabbits died of intestinal bleeding, mesenteric lymph nodes swelling, ileum and cecum mucosa and ileocecal valve swelling in varying degrees, and other organs did not change significantly.

四、诊断。据实验室涂片镜检，细菌学检查结果，结合临床表现及剖检变化，确诊为兔大肠杆菌感染。药敏试验结果为：对庆大霉素、氯霉素、氟哌酸高敏，对卡那霉素、痢特灵、链霉素中敏，对四环素、青霉素、磺胺嘧啶不敏感。

Four 、 diagnosis. According to the laboratory smear microscopy, bacteriological examination results, combined with clinical manifestations and necropsy changes, diagnosed as Escherichia coli infection in rabbits. The results of drug sensitivity test of gentamicin, chloramphenicol and norfloxacin on Gao Min, kanamycin, furazolidone, streptomycin sensitive, not sensitive to tetracycline, penicillin and sulfadiazine.

五、防治措施。将病兔隔离饲养，死兔深埋，对兔舍进行彻底清扫。火碱、百毒杀交替。另外加强通风，保持兔笼干燥。用人工盐5-6克，病情严重者用蓖麻油10-15毫升，加温水人工灌服，同时肌注庆大霉素2万单位/公斤体重，每天2次。饲料中加入氟哌酸，连用4-6天。兔群稳定后，全群接种大肠杆菌灭活疫苗2毫升/只。

Five, prevention and control measures. The rabbits were isolated and reared, the dead rabbits were deeply buried, and the rabbit house was thoroughly cleaned. Caustic soda, disinfection Baidusha alternately. In addition to strengthen the ventilation, keep dry hutch. Artificial salt 5-6 grams, severe cases with castor oil 10-15 ml, with warm water artificial irrigation, while intramuscular injection gentamicin 20 thousand units / kg body weight, 2 times a day. Add norfloxacin feed in 4-6 days. After the rabbit colony stabilized, the whole population was inoculated with inactivated Escherichia coli vaccine 2 ml / ml..

很多养殖户在发现成年兔排出粪便小而坚硬时,只考虑是由于喂精料过多,青饲料不足,缺水等原因引起的便秘,而忽视了大肠杆菌,所以笔者敬告广大养殖户,在长毛兔发生便秘时,应借助科学诊断方法,作出正确诊断,以防误诊,造成更大的经济损失,

Many farmers found in adult rabbit feces are small and hard, only consider is due to feed too much, forage shortage, caused by shortages of constipation, neglect of Escherichia coli, so the author cautioned the majority of farmers in Angora rabbit constipation, should rely on science to make the correct diagnosis method. The diagnosis, to prevent misdiagnosis, resulting in greater economic losses,

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